Diffuse Large B-Cell Lymphoma: Facts About Cancer Statistics (2023)

expand allshow everything

Statistics at a glance

Just look

Once againNew fall rate - SEER 8Rate neuer Fälle - SEER 12Mortality rate — SEER 8 incidence-based mortality5-year relative survival - SEER 8
observedpatterned trendobservedpatterned trendobservedpatterned trendobservedpatterned trend
1975 3.133.13 -- --36,05%41,29%
1976 2,962,95 -- --41,13%41,40%
1977 2.742,78 -- --38,80%41,52%
1978 2.912,96 -- --39,21%41,63%
1979 3.223.14 -- --38,35%41,74%
1980 3.283.35 -- --40,64%41,85%
1981 3,553.56 -- --42,23%41,96%
one thousand nine hundred eighty two 3,853,79 -- --38,95%42,07%
1983 3,824.03 -- --46,07%42,19%
1984 4.434.28 -- --41,71%42,30%
1985 4.524,56 -- --46,95%42,41%
1986 5.074,85 -- --40,53%42,52%
1987 5.255.16 -- --45,58%42,63%
1988 5.425.48 -- --43,84%42,74%
1989 5.695.83 -- --39,88%42,85%
1990 6.256.21 -- --40,60%42,96%
1991 6.236.20 -- --43,39%43,08%
1992 6.136.19 6.076.21 2,802,9840,77%43,19%
1993 6.30 am6.18 6.156.18 2.732.9142,44%43,30%
1994 6.166.17 6.046.15 2.692.8444,62%43,41%
1995 6.426.16 6.226.13 2.822,7842,34%43,52%
1996 5,956.15 5.846.10 2.762.7146,24%46,18%
1997 6.106.14 6.156.07 2,782,6548,60%48,80%
1998 6.086.14 5,956.04 2,942.5951,22%51,36%
1999 5.916.13 5.886.01 2.412.5352,69%53,86%
2000 5.826.12 5.765,99 2.632.4755,30%56,29%
2001 6.326.11 6.165,96 2.682.4258,11%58,65%
2002 5,956.10 5.925,93 2.322.3664,63%60,92%
2003 6.236.09 6.075,90 2.302.3161,65%61,43%
2004 6.236.08 6.195.88 2.292.2561,60%61,94%
2005 5,986.03 5,945,85 1,992.2065,29%62,44%
2006 5.865,97 5.885.82 2.152.1562,64%62,94%
2007 6.025.91 5,975,80 2.082.1062,94%63,43%
2008 5,955.86 5.845.77 1,912.0563,41%63,91%
2009 5.865,80 5.885.74 1,862.0166,23%64,40%
2010 5.835,75 5.775.72 1,931,9665,95%64,87%
2011 5.545,70 5.495.69 1,901,9265,98%65,35%
2012 5.765.64 5.745.66 1,891,8767,73%65,82%
2013 5.415.59 5.585.64 1,711,8367,85%66,28%
2014 5,555.54 5.575.61 1,821,7966,06%66,74%
2015 5.515.49 5.585.58 1,871,75-67,20%
2016 5.405.43 5.565.56 1,751,71-67,65%
2017 5.405.38 5.445.53 1.631,67-68,09%
2018 5.515.33 5.525.51 1,671.63-68,53%
2019 5.135.28 5.305.48 1,591,59-68,97%

New cases are from SEER 12. Deaths are from SEER 8 Incidence-Based Mortality.
All races, both sexes. The prices are adjusted according to age.
The modeled trend lines were calculated using the underlying pricesJoinpoint-Trendanalysesoftware.

New cases are also referred to as incident cases in other publications. New case rates are also called incidence rates.

5 years
relative survival

64,6%2012-2018

Rate of new cases and deaths per 100,000:The rate of new cases of diffuse large B-cell lymphoma was 5.6 per 100,000 men and women per year. The mortality rate was 1.8 per 100,000 males and females per year. These rates are age-adjusted and based on cases and deaths from 2015-2019.

Further information

  • Mortality statistics for diffuse large B-cell lymphoma are based onSEER mortality based on incidence.

Survival Statistics

How many people survive 5 years or more after being diagnosed with diffuse large B-cell lymphoma?

Relative survival is an estimate of the percentage of patients who are expected to survive the effects of cancer. It eliminates the risk of dying from other causes. Because survival statistics are based on large groups of people, they cannot be used to accurately predict what will happen to an individual patient. No two patients are exactly alike, and treatment and response to treatment can vary widely.

Diffuse Large B-Cell Lymphoma: Facts About Cancer Statistics (1)

5 years
relative survival

64,6%

(Video) Understanding Diffuse Large B-Cell Lymphoma with Jennifer Amengual, MD

Based on SEER 17 data from 2012-2018. The gray numbers represent those who died from diffuse large B-cell lymphoma. The green numbers represent those who survived 5 years or more.

Relative 5-year survival by sex, age and race

percent

both genders 64.570123113
male 64.266166032
Women 64.954099603
<55 79.422545075
55–64 70.617646389
65+ 54.770318493
Branco 65.092552343
Negro 60.663914768
Others 63.459658031

SEER 17 2012–2018

Further information

  • More on survival statistics
  • Additional non-Hodgkin lymphoma survival statistics from SEER*Explorer

stage survival

The cancer stage at the time of diagnosis, which refers to the extent of the cancer in the body, determines treatment options and has a strong impact on survival time. The earlier diffuse large B-cell lymphoma is detected, the better a person's chance of survival five years after diagnosis. In diffuse large B-cell lymphoma, 20.5% are diagnosed as stage I. The 5-year relative survival rate for stage I diffuse large B-cell lymphoma is 79.5%.

Percentage of cases and relative 5-year survival by stage at diagnosis: diffuse large B-cell lymphoma

scenariopercent of cases5 years relative survival
Phase I
Limited to a single region
20%79,5%
Stadium II
Inclusion of several regions
20%74,6%
Stove 3
Spread to both sides of the membrane
18%65,5%
Stadium IV
Diffuse or widespread effects
36%54,7%
A foreign
not staged
6%54,9%

Percentage of cases by stage

  • Diffuse Large B-Cell Lymphoma: Facts About Cancer Statistics (2)Stufe I (20%)
    Limited to a single region
  • Diffuse Large B-Cell Lymphoma: Facts About Cancer Statistics (3)Stadium II (20 %)
    Inclusion of several regions
  • Diffuse Large B-Cell Lymphoma: Facts About Cancer Statistics (4)Stadium III (18 %)
    Spread to both sides of the membrane
  • Diffuse Large B-Cell Lymphoma: Facts About Cancer Statistics (5)Stadium IV (36 %)
    Diffuse or widespread effects
  • Diffuse Large B-Cell Lymphoma: Facts About Cancer Statistics (6)Unknown (6%)
    not staged
(Video) Diffuse Large B-Cell Lymphoma (DLBCL) | Aggressive B-Cell Non-Hodgkin’s Lymphoma

5 years relative survival

SEER 17 2012-2018, all races, both sexes from Ann Arbor Stage.
Statistics by stage include only cases coded as lymphoma or lymphoma-CLL/SLL2018 EOD Program Definitions.

Further information

  • Learn more about staging diffuse large B-cell lymphoma
  • Additional non-Hodgkin lymphoma statistics by stage in SEER*Explorer

new cases

who has this cancer

The rate of new cases of diffuse large B-cell lymphoma was 5.6 per 100,000 men and women per year based on age-adjusted cases from 2015 to 2019.

Rate of new cases per 100,000 people by race/ethnicity and sex: diffuse large B-cell lymphoma (DLBCL)

male
all races6.7
non-Hispanic white6.9
non-Hispanic black5,0
Non-Hispanic Asian/Pacific Islander6.3
Non-Hispanic Native American/Alaskan5.1
Spanish7.3
Women
all races4.6
non-Hispanic white4.5
non-Hispanic black3.5
Non-Hispanic Asian/Pacific Islander4.5
Non-Hispanic Native American/Alaskan4.5
Spanish5.4

Diffuse Large B-Cell Lymphoma: Facts About Cancer Statistics (7)Diffuse Large B-Cell Lymphoma: Facts About Cancer Statistics (8)

  • all races
  • non-Hispanic white
  • non-Hispanic black
  • non-Hispanic Asian/
    pacific island
  • Non-Hispanic/
    Alaska Natives
  • Spanish

SEER 22 2015–2019, altersbereinigt

Percentage of new cases by age group: diffuse large B-cell lymphoma

age groupPercentage of new cases
<201,2%
20–345,3%
35–446,2%
45–5411,5%
55–6421,2%
65–7426,2%
75–8420,0%
>848,4%

Diffuse large B-cell lymphoma is most commonly diagnosed in people between the ages of 65 and 74.

middle Ages
no diagnosis

66

(Video) Understanding Diffuse Large B-Cell Lymphoma with Bruce Cheson, MD, FACP, FAAAS, FASCO

SEER 22 2015–2019, all breeds, both sexes

evaluate trends

Changes over time

Tracking new cases, deaths, and survival rates over time (trends) can help scientists understand where progress is being made and where more research is needed to address challenges like improving detection or finding better treatments.

Using statistical models for analysis, age-adjusted rates of new cases of diffuse large B-cell lymphoma decreased by an average of 0.9% each year between 2010 and 2019. Age-adjusted death rates remained stable between 2010 and 2019. Relative one-year survival trends are shown below.

New cases, deaths and 5-year relative survival

New cases are from SEER 8. Deaths are from SEER 8 Incidence-Based Mortality.
All races, both sexes. The prices are adjusted according to age.
The modeled trend lines were calculated using the underlying pricesJoinpoint-Trendanalysesoftware.

SEER 8 percent 5-year relative survival from 1975 to 2014, all races, both sexes.
The modeled trend lines were calculated using the underlying pricesJoinpoint Survival Modeling Software.

Interactive statistics with SEER*Explorer

With SEER*Explorer you can...

  • Create custom charts and tables
  • Download data and images
  • Share links to results

SEER*Explorer is an interactive website that provides easy access to a wide range of SEER cancer statistics. Provides detailed statistics for a cancer site by gender, race, calendar year, age, and for a selected number of cancer sites by stage and histology.

Explore additional non-Hodgkin lymphoma statistics

(Video) High Grade Diffuse large B-cell Lymphoma: Carole's story

More about this cancer

Non-Hodgkin's Lymphoma

Figure: Lymph nodes above and below the diaphragm

Diffuse Large B-Cell Lymphoma: Facts About Cancer Statistics (9)

Illustration: This image shows the lymph nodes above and below the diaphragm. It also shows the lymphatic vessels, tonsils, thymus gland and spleen.

Lymphoma is a cancer that begins in the cells of the lymphatic system. The lymphatic system is part of the immune system, which helps the body fight infection and disease. Because lymphoid tissue is found throughout the body, lymphoma can start almost anywhere.

The two main types of lymphoma are Hodgkin's lymphoma and non-Hodgkin's lymphoma (NHL). These can occur in both children and adults.

There are many different types of NHL, made up of different types of white blood cells (B cells, T cells, NK cells). Most types of NHL are made up of B cells. NHL can be sluggish (slow growing) or aggressive (fast growing). The most common types of NHL in adults are diffuse large B-cell lymphoma, which is usually aggressive, and follicular lymphoma, which is usually indolent.

Further information

  • Learn more about non-Hodgkin lymphoma

More information

Here are some resources to learn more about non-Hodgkin lymphoma.

  • Learn more about risk factors for non-Hodgkin's lymphoma
  • Learn more about non-Hodgkin lymphoma symptoms and diagnosis
  • Learn more about treatment options for non-Hodgkin lymphoma
  • More about clinical trials
  • More about cancer prevention

references

All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found thereSEER*Batedor.

suggested quote

All material in this report is in the public domain and may be reproduced or copied without permission; however, a reference to the source is desired.

SEER cancer statistics: Diffuse large B-cell lymphoma, National Cancer Institute. Bethesda, MDhttps://seer.cancer.gov/statfacts/html/dlbcl.html

These statistics focus on vital statistics based on the US population. Because these statistics are based on large groups of people, they cannot be used to accurately predict what will happen to an individual patient. To see custom stats, browseSEER*Batedor. To view statistics for a specific condition, go toState Cancer Profiles.

(Video) Diffuse Large B Cell Lymphoma From Diagnosis to Treatment

The statistics presented in this Statistical Data are based on the latest available data, most of which can be found atSEER*Batedor. In some cases, different annual periods can be used.

Estimates of new cases and deaths for 2022 are projections from the American Cancer Society (ACS) based on previously published data.

Cancer is a complex subject. There is a wide range of information. These statistics do not address causes, symptoms, diagnosis, treatment, follow-up care, or decision-making, although links are provided to information in many of these areas.

FAQs

What are the statistics for diffuse large B cell lymphoma? ›

The estimated rate for diffuse large B-cell lymphomas is approximately 4.68 cases per 100,000 person-years. It is estimated that approximately 80,470 new cases of NHL will be diagnosed and 20,250 patients will die from NHL in 2022, despite currently available treatment.

Is diffuse large B cell lymphoma cancerous? ›

Diffuse large B cell lymphoma (DLBCL) is a type of non-Hodgkin lymphoma (NHL). NHL is a cancer of the lymphatic system. It develops when the body makes abnormal B lymphocytes.

What is the survival rate for diffuse large B cell lymphoma? ›

The overall 5-year relative survival rate for people with NHL is 73%. But it's important to keep in mind that survival rates can vary widely for different types and stages of lymphoma.
...
Diffuse large B-cell lymphoma.
SEER Stage5-Year Relative Survival Rate
Regional73%
Distant57%
All SEER stages combined64%
1 more row
Mar 2, 2022

Is diffuse B cell lymphoma rare? ›

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma (NHL) in the United States and worldwide, accounting for about 22 percent of newly diagnosed cases of B-cell NHL in the United States. More than 18,000 people are diagnosed with DLBCL each year.

Can you survive stage 4 diffuse large B-cell? ›

Diffuse large b cell lymphoma stage 4 survival rate for 5 years by stage according to SEER: Localized: 73% Regional: 73% Distant: 57%

How fast does DLBCL spread? ›

They usually grow quite quickly, over just a few weeks. Sometimes, DLBCL can develop in lymph nodes deep inside your body where they can't be felt from the outside. The swollen nodes can form large lumps – known as 'bulky disease'. DLBCL can also develop outside lymph nodes, called 'extranodal' disease.

Is diffuse large B-cell lymphoma terminal? ›

It can be fatal if left untreated. All lymphomas, including DLBCL, affect the organs of your lymphatic system. Your lymphatic system is what allows your body to fight infections.

Can you survive stage 4 B-cell lymphoma? ›

Stage 4 non-Hodgkin's diffuse large B-cell lymphoma has a five-year relative survival rate of 57%15. Stage 4 non-Hodgkin's follicular lymphoma has a five-year relative survival rate of 86%15. Stage 4 Hodgkin's lymphoma has a five-year relative survival rate of 82%16.

What are 3 facts about lymphoma? ›

Age increases the risk of most cancers, including lymphoma. Sex is a risk factor; males are more likely than females to be diagnosed. Race increases risk; Caucasians are more likely to develop lymphoma. Previous cancer treatment with chemotherapy and radiation can increase risk.

What are the survival statistics for lymphoma? ›

The overall 5-year survival rate for people with NHL in the United States is 73%. For stage I NHL, the 5-year survival rate is more than 84%. For stage II the 5-year survival rate is 77%, and for stage III it is more than 71%. For stage IV NHL, the 5-year survival rate is almost 64%.

What causes death from lymphoma? ›

People with NHL most often die from infections, bleeding or organ failure resulting from metastases. A serious infection or sudden bleeding can quickly lead to death, even if someone doesn't appear very ill.

What percent of DLBCL patients relapse? ›

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Approximately 30% to 40% of patients will develop relapsed/refractory (R/R) DLBCL, leading to significant morbidity and mortality.

What is the risk factor for diffuse large B-cell lymphoma? ›

Infections that weaken the immune system

Infection with human immunodeficiency virus (HIV), also known as the AIDS virus, can weaken the immune system. HIV infection is a risk factor for developing certain types of NHL, such as primary CNS lymphoma, Burkitt lymphoma, and diffuse large B-cell lymphoma.

How often does diffuse large B-cell lymphoma come back? ›

Despite a general favourable outcome in limited stage diffuse large B-cell lymphoma (DLBCL), relapses occur in about 10 to 20% of patients.

Videos

1. Diffuse Large B-Cell Lymphoma Diagnosis& Treatment | Aggressive B-Cell Non-Hodgkin’s Lymphoma
(Medicosis Perfectionalis)
2. Update on Diffuse Large B-Cell Lymphoma | LRF Webinars
(Lymphoma Research Foundation)
3. Cancer Survivor Story: Non-Hodgkin Lymphoma, Stage 4 (Diffuse Large B-Cell and Burkitt Lymphoma)
(The Patient Story)
4. Diffuse large B cell lymphoma
(Cancer Therapeutics)
5. NCCN Patient Webinar: Diffuse Large B-Cell Lymphoma
(NCCN)
6. DLBCL in 2023: Top Docs Discuss the LATEST in Diffuse Large B-Cell Lymphoma | Treatments & Research
(The Patient Story)
Top Articles
Latest Posts
Article information

Author: Merrill Bechtelar CPA

Last Updated: 03/02/2023

Views: 5922

Rating: 5 / 5 (70 voted)

Reviews: 85% of readers found this page helpful

Author information

Name: Merrill Bechtelar CPA

Birthday: 1996-05-19

Address: Apt. 114 873 White Lodge, Libbyfurt, CA 93006

Phone: +5983010455207

Job: Legacy Representative

Hobby: Blacksmithing, Urban exploration, Sudoku, Slacklining, Creative writing, Community, Letterboxing

Introduction: My name is Merrill Bechtelar CPA, I am a clean, agreeable, glorious, magnificent, witty, enchanting, comfortable person who loves writing and wants to share my knowledge and understanding with you.